The aim of this study is to identify key barriers that hinder adoption of energy efficiency measures in the industrial and commercial sectors in Ukraine. A field survey questionnaire was developed that permits the 500 industrial and commercial enterprises to reveal specific barriers to increasing energy efficiency, comparing these barriers among each other to rank them and to study investment behavior of the enterprises. Enterprises to survey were chosen with two-stage quota sample that accounts for their energy consumption and GHG emissions, among other factors. The sample included industrial and non-industrial energy intensive enterprises of all the regions of Ukraine.